CD34 cell

Authors

Affiliations

Nathaniel Yomogida, B.S., SPT

Doctor of Physical Therapy

B.S. in Kinesiology

Chloë Kerstein, B.S., SPT

Doctor of Physical Therapy

B.A. in Neuroscience

Overview

Class of proteins first discovered on hematopoietic (blood cell production) progenitors and stem cells¹
Has been used as a hematopoietic stem and progenitor cell marker¹
Found in low frequencies in peripheral blood, can be increased by cytokines and chemotherapy¹
Can also be found on vascular endothelial cells, as well as on muscle satellite cells, keratocytes, interstitial cells, fibrocytes, epithelial progenitors and endothelial junctions between adjacent endothelial cells of humans¹
Muscle satellite cells and epidermal precursors can be identified with CD34¹

Clinical significance

Can be used as a measure of contusion healing as seen in our journal club article.

References

Rodrigues CR, Moga S, Singh B, Aulakh GK. CD34 Protein: Its expression and function in inflammation. Cell and Tissue Research. 2023;393(3):443-454. doi:10.1007/s00441-023-03811-4

Citation

For attribution, please cite this work as:

Yomogida N, Kerstein C. CD34 cell. https://yomokerst.com/The Archive/Microbiology/Cells/CD34_cell.html